Grapefruit Seed Extract is highly concentrated. It provides 45% polyphenols. Polyphenols help support healthy microbial and fungal balance within the gastrointestinal tract.* They assist the body in maintaining healthy bacteria in the G.I. tract while helping the body expel unwanted microorganisms like bacteria, protozoa and fungus.* A preliminary clinical trial reported that grapefruit seed extract supplements helped support healthy G.I. function and comfort. An in vitro study using human skin fibroblast cells indicated that grapefruit seed extract promoted healthy gram-positive and gram-negative balance. Other studies support these findings, citing that grapefruit seed extract promotes a healthy environment when exposed to a wide range of bacterial biotypes.*